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Holistic medicine practitioner · Ocala, FL

Low-Dose Naltrexone Therapy in Ocala, FL

Low-dose naltrexone (LDN) is a small daily dose of a well-established medication that gently raises endorphins to calm an overactive immune system. At Symphony Healthcare, Debora Donahue, APRN-BC uses LDN as part of an integrative plan for autoimmune, thyroid, and inflammatory conditions, with transparent self-pay fees and telemedicine options.

Immune-balancing therapyGentle, low daily doseServing Ocala since 2012
4.8from 128 Google reviews
Woman holding a low-dose naltrexone tablet and a glass of water in Ocala, FL
An integrative approach

What Is Low-Dose Naltrexone?

Low-dose naltrexone is naltrexone taken in very small daily doses, far below the amount used for its original purpose. At these doses it briefly blocks endorphin receptors, prompting the body to make more of its own endorphins. Those endorphins help regulate the immune system, lower inflammation, and ease symptoms of autoimmune and thyroid conditions.

Naltrexone was first approved to treat opioid and alcohol dependence. Researchers later found that a fraction of that dose can quiet an overactive immune response instead. At Symphony Healthcare we prescribe and monitor LDN as one tool inside our integrative medicine clinic in Ocala, pairing it with the labs, nutrition, and hormone support that address the root of your symptoms.

Low-dose naltrexone consultation with a satisfied patient in Ocala, FL
We can help

Conditions Low-Dose Naltrexone Can Help Treat

Because it works by balancing immune activity and lowering inflammation, LDN can ease a wide range of chronic conditions. It is not a cure, but for many patients it makes symptoms more manageable as part of an integrative plan built around lab testing and root-cause care.

Autoimmune disorders

Conditions like lupus, multiple sclerosis, and Hashimoto's involve an immune system that attacks healthy tissue. LDN helps calm that overactivity and can reduce flares.

Rheumatoid arthritis

By lowering inflammation, LDN may ease joint pain and stiffness for patients living with rheumatoid arthritis alongside their standard care.

Thyroid disorders

For autoimmune thyroid conditions, LDN can support immune balance and complement a full thyroid protocol and hormone optimization.

Crohn's disease

LDN has been studied for inflammatory bowel conditions and may help reduce the immune-driven inflammation behind Crohn's symptoms.

Digestive disorders

When gut inflammation is part of the picture, LDN can be paired with functional gut care to help restore comfort and balance.

Chronic pain and fatigue

By raising endorphins, LDN may improve energy, mood, and pain tolerance for patients dealing with persistent fatigue and discomfort.
The Symphony difference

Why Patients Choose LDN at Symphony Healthcare

Low-dose naltrexone works best when it is part of a plan, not a standalone prescription. We pair it with targeted testing and the same root-cause attention we bring to every patient, so the therapy fits your body and your goals rather than a template.

Immune system support

LDN helps regulate immune activity and reduce unnecessary inflammation, which can ease symptoms of autoimmune disorders over time.About naltrexone: MedlinePlus

Gentle, affordable therapy

Because it is used in very small doses, LDN is generally well tolerated and offers meaningful benefits without the heavy side effects common to stronger drugs.

Improved energy and mood

By raising the body's own endorphins, LDN can support steadier energy, a more stable mood, and an overall sense of well-being.On endorphins: NIH MedlinePlus

Tailored care from an expert team

Debora Donahue, APRN-BC reviews your history and labs before prescribing, so LDN is dosed and monitored as part of a plan built specifically for you.
How it works

Starting Low-Dose Naltrexone at Symphony

LDN is prescribed carefully and started low, then adjusted as your body responds. The path is the same for every patient, personalized by your history and labs, so you always know what happens next and why.

  1. Consultation and history

    A free consultation call, then a first visit reviewing your symptoms, diagnoses, medications, and supplement history.

  2. Targeted testing

    Debora orders the labs that clarify whether LDN fits your picture and confirms it is safe alongside your other medications.

  3. Careful, low-dose start

    You begin at a low dose from a compounding pharmacy, taken once daily, so your body can adjust gently.

  4. Monitoring and adjustment

    We follow up in office or by telemedicine to track your response and fine-tune the dose until it is working for you.

Transparent self-pay fees

What Low-Dose Naltrexone Costs in Ocala

Symphony Healthcare, Inc. is a self-pay medical practice and does not participate with or bill any insurance companies. Visit fees are published in advance, so there are no surprise statements, just clear prices and a plan you approve before you start.

$275Initial visit

Full history review, exam, and lab orders

$125Routine follow-up

LDN dose checks and adjustments

$200Extended visit

Longer visits for complex reviews

Telemedicine visits can be scheduled for follow-ups.

Your total cost depends on:

  • Visit frequency and follow-up cadence
  • Lab panels, with self-pay rates through Access Lab
  • The cost of your LDN prescription at a compounding pharmacy
  • Whether your plan includes other supplements or hormone support

The free consultation is the easiest way to get an exact picture for your situation.

Debora Donahue, APRN-BC, founder of Symphony Healthcare in Ocala, FL
Your provider

Meet Your Provider: Debora Donahue, APRN-BC

Debora Donahue, APRN-BC founded Symphony Healthcare in 2012 after years of watching rushed appointments miss what mattered. She is a Florida-licensed APRN, board certified through the AANP as a Family Nurse Practitioner, with more than 25 years of clinical experience and deep training in functional and integrative medicine. She prescribes and monitors low-dose naltrexone the way she practices everything: listen first, test for root causes, and build the plan around the person in front of her.

APRN-BCAANP Family Nurse PractitionerFounder, Symphony Healthcare, 2012
From Google reviews

What Patients Say

Staff and Debora are great. The LDN I am on has placed me in remission for a year and a half from my UC. What a game changer
Debra Jaroszewicz
she believes in helping you figure our the root cause of your symptoms and is not quick to prescribe you medicines without investigating your issues in detail, analyzing blood work and adjusting your diet where needed.
PalBennett
Good questions

Frequently Asked Questions

How does low-dose naltrexone work?
LDN works by gently and briefly increasing your body's own endorphin production. Those endorphins help regulate the immune system, lower inflammation, and change how the body responds to fatigue, pain, or mood shifts. Over time, that support can improve energy, restore balance, and ease symptoms of autoimmune and inflammatory conditions.
Are there side effects or precautions with LDN?
Most patients tolerate low-dose naltrexone very well. Some notice temporary sleep disturbances, vivid dreams, or mild fatigue during the first week. These usually resolve within seven to ten days, and dosing adjustments help if needed. LDN is not recommended during pregnancy or breastfeeding, and it cannot be taken with opioid medications.
Can I take LDN with my other prescriptions?
Yes, in most cases. LDN is often used alongside thyroid medication and hormone optimization therapy. The one firm exception is opioids, which cannot be combined with naltrexone. Debora reviews your full medication list before prescribing to confirm LDN is safe and effective as part of your personalized plan.
How long does it take to notice the benefits of LDN?
Many patients feel subtle improvements in sleep, energy, or mood within the first few weeks. For autoimmune disorders or chronic inflammation, results can take longer, because the immune system needs time to respond. We monitor your progress and adjust your dose to keep you moving toward the best result.
How much does low-dose naltrexone therapy cost in Ocala?
Symphony Healthcare is a self-pay practice with transparent visit fees: $275 for the initial visit, $125 for routine follow-ups, and $200 for extended visits. Your LDN prescription is filled at a compounding pharmacy, and lab work uses self-pay rates through Access Lab. The free consultation gives you an exact picture for your plan.
Do you offer LDN by telemedicine?
Yes. After an initial visit and any needed labs, follow-up visits for low-dose naltrexone can be scheduled by telemedicine. That makes ongoing dose monitoring workable for patients across Marion County, including Belleview, Silver Springs Shores, and The Villages.

Book Your Low-Dose Naltrexone Consultation in Ocala

Start with a free, no-pressure phone call, about 10 minutes, to see if low-dose naltrexone fits your health picture. If it does, we schedule your first visit and map out the testing and dosing from there.

Monday through Thursday, 8am to 5pm. 1329 SE 25th Loop, Suite 102, Ocala, FL 34471.